Vilsmeier-Haack Reaction

Vilsmeier-Haack Reaction

Vilsmeier-Haack Reaction

Vilsmeier-Haack reaction is a common method to introduce a formyl group into electron rich aromatic compound using DMF, an acid chloride, and aqueous work-up. It is also applicable to electron rich alkenes.
Vilsmeier-Haack Reaction


Mechanism of Vilsmeier-Haack Reaction

The possible mechanism is given below-
Mechanism of Vilsmeier-Haack Reaction


Examples of the Vilsmeier-Haack Reaction

Examples of Vilsmeier-Haack Reaction