Pechmann Reaction

Pechmann Reaction

Pechmann Reaction

Pechmann condensation discovered by Hans von Pechmann in 1883 is condensation of phenols with β-keto esters or carboxylic acids under acidic conditions to form coumarins. The acid catalysts used for the Pechmann condensation reaction are concentrated sulphuric acid, trifluoroacetic acid (TFA), phosphotungstic acid, TiCl4, P2O5, ZrCl4, Nafion resin, HClO4/SiO2, SnCl2·2H2O, zirconium phosphor-tungstate, deep eutectic solvents, ionic liquids, etc.

Pechmann Reaction, Pechmann Condensation: Coumarin Synthesis

Mechanism of Pechmann Reaction

Pechmann Reaction Mechanism, Pechmann Condensation: Coumarin Synthesis

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