Why TMS Used As Standard Compound ?

TMS used as a reference compound because of the following reasons-

1. It has 12 equivalent protons which give an intense signal. Therefore, even a small quantity of it gives a measurable signal.
2. Silicon is less electronegative than carbon, protons of TMS are therefore, highly shielded. They give a NMR signal in a region where few other protons absorb. Hence, signal of the reference compound seldom interferes with the signals from other protons.

3. It is inert and volatile and can therefore, be easily removed by evaporation after the experiment is over.
Thus, advantage of using TMS as reference is that it gives a strong and sharp NMR signal in a region where only a very few kinds of other protons absorb.

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