Rupe Rearrangement Rupe Rearrangement Rupe Rearrangement The acid catalyzed thermal rearrangement of tertiary α‐acetylenic (terminal) alcohols into the corresponding α,β‐unsaturated ketones is known as the Rupe rearrangement. Mechanism of Rupe Rearrangement The possible mechanism is given below- Applications of Rupe Rearrangement