Reimer-Tiemann Reaction
Formylation of phenol with chloroform in alkaline solution at about 60°C is known as Reimer-Tiemann Reaction. A mixture of ortho and para isomers are obtained but the ortho isomer predominates and para isomers predominates only when one of the ortho position is occupied.
When CCl4 is used in place of chloroform, an acid (-COOH) group is introduced at ortho position of phenol.




When CCl4 is used in place of chloroform, an acid (-COOH) group is introduced at ortho position of phenol.