M Pharmacy Entrance Exam Model Question
M Pharmacy Entrance Exam Model Question With Answer
1. Acetylcholine and physostigmine are examples of --- type drug interaction.
A. SynergismB. Addition
C. Potentiation
D. Antagonism
Answer
C. Potentiation2. Drug having high affinity but low intrinsic activity is called
A. Partial agonistB. Antagonist
C. Non-competitive antagonism
D. Competitive antagonism
Answer
A. Partial agonist3. Sodium methoxide is standardized by
A. Oxallic acidB. Perchloric acid
C. Acetic acid
D. Benzoic acid
Answer
D. Benzoic acid4. Which one of the following propellant is used in the aerosol for oral use?
A. PropaneB. Oxygen
C. Methane
D. Trichloro monofluoro methane
Answer
D. Trichloro monofluoro methane5. How do you calculate the rate of excretion by kidneys
A. Rate of filtration – rate of secretion – rate of absorptionB. Rate of filtration + rate of secretion – rate of absorption
C. Rate of filtration + rate of secretion + rate of absorption
D. Rate of filtration – rate of secretion + rate of absorption
Answer
B. Rate of filtration + rate of secretion – rate of absorption6. The release of maintenance dose in sustained release dosage form should follow
A. Zero-order kineticsB. First-order kinetics
C. Second-order kinetics
D. Pseudo-order kinetics
Answer
A. Zero-order kinetics7. Advantage of salmeterol over salbutamol is its
A. Shorter duration of actionB. More potency
C. Longer duration of action
D. Lesser cardiac effects
Answer
C. Longer duration of action8. To study the stress and rate of shear, the phenomenon of converting gel to sol is known as
A. Plastic flowB. Pseudo plastic flow
C. Thixotropy
D. Dilatant flow
Answer
B. Pseudo plastic flow9. Which hormone is released at all postganglionic sympathetic fiber?
A. AdrenalineB. Dopamine
C. Noradrenaline
D. Isoprenaline
Answer
A. Adrenaline10. Biosynthesis of isothiocyanate aglycone follows
A. Acetate pathwayB. Mevalonate pathway
C. Shikkimic pathway
D. None of the above
Answer
A. Acetate pathway11. Sodium starch glycollate is used as
A. GlidantB. Lubricant
C. Disintigrant
D. Binder
Answer
C. Disintigrant12. Which of the following surfactant also possess antibacterial activity?
A. Glyceryl monostearateB. Quaternary ammonium compounds
C. Sodium oleate
D. Sodium lauryl sulphate
Answer
B. Quaternary ammonium compounds13. How much solvent is required to dissolve a sparingly soluble salt?
A. 10 to 30 partsB. 1 to 10 parts
C. 100 to 150 parts
D. 100 to 1000 parts
Answer
D. 100 to 1000 parts14. Drug of choice in motion sickness is
A. AtropineB. Scopolamine
C. Carbamazepine
D. Metoclopromide
Answer
B. Scopolamine15. Which of the following intravenous anesthetic agents is contraindicated in epileptic patients posted for general anesthesia?
A. KetamineB. Thiopentone
C. Propofol
D. Midazolam
Answer
A. Ketamine16. Pseudoplastic flow is typically exhibited by
A. EmulsionB. Polymer solution
C. Suspension
D. Ointment
Answer
B. Polymer solution17. Following is not a derived property of powder
A. Surface areaB. Particle size
C. Bulk density
D. None
Answer
C. Bulk density18. In a patient of chronic asthma on treatment with theophyline, which of the following should not be used to treat his upper respiratory tract infection?
A. AmpicillinB. Cephalexin
C. Erythromycin
D. All
Answer
C. Erythromycin19. All of the following adverse effects are associated with the use of proton pump inhibitors except
A. Community acquired pneumoniaB. Clostridium difficile infection
C. Osteoporosis leading to hip fracture
D. Hypothyroidism
Answer
D. Hypothyroidism20. The solvent not used in IR spectroscopy is
A. ChloroformB. Carbon tetra chloride
C. Carbon disulfite
D. Water
Answer
D. Water21. A person consumes large quantities of alcohol daily since 20 years. He is physically dependent on alcohol. Drug that should not be given to this person is
A. DisulfiramB. Acamprosate
C. Naltrexone
D. Chlordiazepoxide
Answer
A. Disulfiram22. Empty capsule has moisture content in the range of
A. 60%B. 12%-15%
C. 50%- 70%
D. 30%
Answer
B. 12%-15%23. Which treatment is used for solubility of gelatin?
A. HeatB. Formalin
C. Water
D. Alcohol
Answer
B. Formalin24. Duhring’s rule is related to
A. CrystallizationB. Distillation
C. Filtration
D. Size reduction
Answer
B. Distillation25. The transition from excited state to ground state is called
A. ExcitationB. Absorption
C. Relaxation
D. Scatterin
Answer
C. Relaxation26. Hammer mill works by following principle
A. ImpactB. Attrition
C. Compression
D. None
Answer
A. Impact27. Select a mill for a low melting drug
A. Hammer millB. Roller mill
C. Ball mill
D. Fluid energy mill
Answer
D. Fluid energy mill28. Deficiency of which of the following causes respiratory distress syndrome?
A. PhosphetidylserineB. Sphingomyelin
C. Plasmogens
D. Dipalmitoyllecithin
Answer
D. Dipalmitoyllecithin29. Which of the following is not factor or renal excrection
A. Blood flow to kidneysB. Urine pH
C. Blood pH
D. Disease condition
Answer
C. Blood pH30. The most commonly used humectants in tooth paste includes
A. GlycerolB. Sorbitol
C. Both a & b
D. None of these
Answer
C. Both a & b31. Calcium channel blocker with predominant peripheral action is
A. NicardepineB. Verapamil
C. Nifedepine
D. Diltiazem
Answer
C. Nifedepine32. Which antihypertensive drug has to be avoided in a diabetic patient ho is taking insulin?
A. GuanethidineB. α-methyl dopa
C. Propranolol
D. Hydralazine
Answer
C. Propranolol33. Flame photometry cannot be used for
A. BariumB. Calcium
C. Selenium
D. Sodium
Answer
C. Selenium34. The suckers in leech are
A. One pairB. Two pair
C. Three pair
D. Four pair
Answer
A. One pair35. The following is an example for atomic spectra
A. UV spectraB. Colorimetry
C. Flourimetry
D. Flame photometry
Answer
D. Flame photometry36. In HDL ----- of triacylglycerol is present
A. 88%B. 55%
C. 12%
D. 98%
Answer
A. 88%37. For effective screening of all bacteria for sterilization of liquids the membrane pore size is
A. 0.2µmB. 0.45µm
C. 0.8µm
D. 1.2µm
Answer
A. 0.2µm38. The steroid having role in promoting maturation of the lung in foetus is
A. AndrogenB. Estrogen
C. Progestine
D. Glucocorticoids
Answer
D. Glucocorticoids39. Which of the following receptor shows the slowest response?
A. GPCRB. Ion channel
C. Enzyme linked
D. Steroid receptor
Answer
B. Ion channel40. Aspirin should not be used in
A. GoutB. Myocardial infarction
C. Both a and b
D. None of the above
Answer
A. Gout41. Ursodeoxycholic acid is used in the treatment of
A. JaundiceB. Urinary tract infection
C. Malaria
D. Gastrointestinal tract infection
Answer
A. Jaundice42. Most common Phase-II reaction is
A. Sulfate conjugationB. Glucuronide conjugation
C. α amino acid conjugation
D. Methylation
Answer
B. Glucuronide conjugation43. Acetylcholine and physostigmine are examples of ----- type drug interaction
A. SynergismB. Addition
C. Potentiation
D. Antagonism
Answer
C. Potentiation44. Example of stimulant purgative is
A. Ispaghula huskB. Cisapride
C. Senna
D. Lactulose
Answer
C. Senna45. Bioassays are carried out to
A. Measure the pharmacological activity of a drugB. Avoid clinical trials for new drugs
C. Detect the impurity in a given drug
D. Screen from pharmacogenetic influences of new drugs
Answer
A. Measure the pharmacological activity of a drug46. Following drugs have volume of distribution more than 200
A. WarfarinB. Digoxin
C. Alcohol
D. None
Answer
B. Digoxin47. In gas chromatography sample must be in
A. Solid stateB. Gas state
C. Liquid state
D. Crystal
Answer
B. Gas state48. Paracetamol is assayed by
A. Ceric ammonium sulphateB. I2
C. HPLC
D. KIO3
Answer
A. Ceric ammonium sulphate49. Toxoids are used for
A. TuberculosisB. Typhoid
C. Enteric fever
D. Diphtheria
Answer
D. Diphtheria50. Magnesium aluminium silicate is used as
A. Oral rehydration saltB. Absorbent
C. Antimotility agent
D. Anti emetic agent
Answer
B. Absorbent Share
