Curtius Reaction

Curtius Reaction

Curtius Reaction

Curtius raction is a thermal decomposition of acyl azide in an inert solvent to isocyanate. Curtius reaction is also known as Curtius degradation.
Isocyanates are subjected to attack by various nucleophiles namely alcohols, water, and amines which gives urethane, amine and urea derivative resectively.
Curtius Reaction

Mechanism of Curtius Reaction

The possible mechanism is given below-
Mechanism of Curtius Reaction
Isocyanate with water
Mechanism of Curtius Reaction with water

Applications of the Curtius Reaction

Applications of Curtius Reaction