Curtius Reaction
Curtius raction is a thermal decomposition of acyl azide in an inert solvent to isocyanate. Curtius reaction is also known as Curtius degradation.
Isocyanates are subjected to attack by various nucleophiles namely alcohols, water, and amines which gives urethane, amine and urea derivative resectively.
Isocyanate with water
Isocyanates are subjected to attack by various nucleophiles namely alcohols, water, and amines which gives urethane, amine and urea derivative resectively.
Mechanism of Curtius Reaction
The possible mechanism is given below-Isocyanate with water
