Synthesis of Estrone

Synthesis of Estrone

Synthesis of Estrone

Structure of EstroneThe name estrone was derived from the chemical terms estrin (estra-1,3,5(10)-triene) and ketone.
Estrone is also known as estra-1,3,5(10)-trien-3-ol-17-one, is a naturally occurring estrane steroid with double bonds at the C1, C3, and C5 positions, a hydroxyl group at the C3 position, and a ketone group at the C17 position.
It is primarily synthesized in peripheral tissues (like fat cells, muscle, and liver) from androgen precursors (like androstenedione) through the action of an enzyme called aromatase. The conversion of androgen to estrogen in peripheral tissues makes estrone crucial for providing some estrogenic activity in postmenopausal women.

Biosynthesis of Estrone (Johnson Synthesis)

Biosynthesis of Estrone

X

Hi, Welcome to Maxbrain Chemistry.
Join Telegram Channel to get latest updates.
Join Now

Daily
Quiz

Admission Alert ⚠️

✦ B.Sc. All Semester


✦ CBSE:12th Complete Course Annual Exam 2026


✦ CBSE:12th Compartmental Exam July 2025


✦ NIOS:Sr. Secondary Complete Course October 2025


Complete Syllabus | PYQs | MCQs | Assignment


Online Class: 1st June 2025


Call or WhatsApp